Faculty
FLORIDA STATE / PEOPLE / FACULTY
Dr. Lissa C. Anderson, Research Faculty II
Contact Information
| anderson@magnet.fsu.edu | ||
| Office | NHMFL FSU | 850.644.1756 |
Research Interest
Dr. Lissa Anderson is Research Faculty and the Director of Biological Applications for the Ion Cyclotron Resonance User Facility of the National High Magnetic Field Laboratory (MagLab) located at Florida State University. The facility is charged with developing and exploiting the unique capabilities of high-field Fourier-transform ion cyclotron resonance mass spectrometry (FT-ICR MS) and leads the word in instrument and technique development as well as well as novel applications of FT-ICR MS.
Current Research
Dr. Anderson’s research is organized under several interrelated topics of top-down proteomics (i.e., intact proteoform analysis). These include development and application of new technologies to perform ion-ion chemistry inside the mass spectrometer to improve proteoform detection sensitivity and primary structure determination. She has also been privileged to work with dozens of MagLab users and collaborators, in the US and abroad, to develop and apply optimized top-down proteomic strategies to achieve a truly molecular-level understanding of biological phenomena.
Publications
Publications
| Lin, Y.; Agarwal, A.M.; Anderson, L.C.; Marshall, A.G., Discovery of a biomarker for β-Thalassemia by HPLC-MS and improvement from Proton Transfer Reaction – Parallel Ion Parking, JMSACL, 28, 20-26 (2023) https://doi.org/10.1016/j.jmsacl.2023.01.004 |
| Adams, L.M.; DeHart, C.J.; Drown, B.S.; Anderson, L.C.; Bocik, W.; Boja, E.S.; Hiltke, T.M.; Hendrickson, C.L.; Rodriguez, H.; Caldwell, M.; Vafabakhsh, R.; Kelleher, N.L., Mapping the KRAS Proteoform Landscape in Colorectal Cancer Identifies Truncated KRAS4B that Decreases MAPK Signaling, Journal of Biological Chemistry, 299 (1), 102768 (2023) https://doi.org/10.1016/j.jbc.2022.102768 – Data Set |
| Popovic, Z.; Anderson, L.C.; Zhang, X.; Butcher, D.S.; Blakney, G.T.; Zubarev, R.A.; Marshall, A.G., Analysis of Isotopically Depleted Proteins Derived from Escherichia coli and Caenorhabditis elegans Cell Lines by Liquid Chromatography 21 T Fourier Transform-Ion Cyclotron Resonance Mass Spectrometry, Journal of the American Society for Mass Spectrometry, 34 (2), 137-144 (2023) https://doi.org/10.1021/jasms.2c00242 |
| Melani, R.D.; Gerbasi, V.R.; Anderson, L.C.; Sikora, J.W.; Toby, T.K.; Hutton, J.E.; Butcher, D.S.; Negrao, F.; Seckler, H.S.; Srzentic, K.; Fornelli, L.; Camarillo, J.M.; LeDuc, R.D.; Cesnik, A.J.; Lundberg, E.; Greer, J.B.; Fellers, R.T.; Robery, M.T.; DeHart, C.J.; Forte, E.; Hendrickson, C.L.; Abbatiello, S.E.; Thomas, P.M.; Kokaji, A.I.; Levitsky, J.; Kelleher, N.L., The Blood Proteoform Atlas: A Reference Map of Proteoforms in Human Hematopoietic Cells, Science, 375 (6579), 411-418 (2022) https://doi.org/10.1126/science.aaz5284 – Data Set |
| Lin, Y.; Agarwal, A.M.; Marshall, A.G.; Anderson, L.C., Characterization of Structural Hemoglobin Variants by Top-Down Mass Spectrometry and R Programming Tools for Rapid Identification, Journal of the American Society for Mass Spectrometry, 33 (1), 123-130 (2022) https://doi.org/10.1021/jasms.1c00291 – Data Set 1, Data Set 2 |